Successful management of poisoned patients involves adapting the ABCDE approach to include toxicological considerations (including expedient recognition of various classic toxidromes), performing a toxicology-focused history and physical examination, and tailoring management based on an individualized risk assessment of each patient. Although fewer than 1% of poisonings are fatal, acute poisoning can be a challenging medical emergency.
This article provides a general approach to patients with known or suspected acute poisoning from exposure to a wide variety of potentially toxic substances, including medications, recreational drugs, and common household products.
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